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The cost of ezetimibe with or without insurance can depend on several factors. It might be lowered by using a coupon. Ezetimibe can also be taken to treat inherited conditions like heterozygous hypercholesterolemia (a genetic condition that causes high cholesterol). It reduces the amount of LDL cholesterol in the blood. Ezetimibe is the active ingredient in the brand name medication Zetia. Zetia (ezetimibe) can be taken as a tablet with or without food. EZETIMIBE (Generic for ZETIA) QTY 90 10 MG Tablet Near 77381 Add to Medicine Chest Set Price Alert EZETIMIBE (ez ET i mibe) treats high cholesterol. It works by reducing the amount of cholesterol absorbed from the food you eat. This decreases the amount of bad cholesterol (such as LDL) in your blood. Changes to diet and exercise are often combined with this medication. Ezetimibe is a generic tablet prescribed for reducing high cholesterol in adults and certain children. It's available as the brand-name drug Zetia. The cost of ezetimibe with and without … Ezetimibe (Zetia) is an expensive drug used to lower blood cholesterol for patients who are at risk of getting heart disease or a stroke. It is only for patients whose cholesterol level is not controlled by diet. Zetia (ezetimibe) is used to treat high cholesterol. Includes Zetia side effects, interactions and indications.