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The lowest available price for Advair diskus 100 mcg/50 mcg is $0.65 per dose for 180 doses at PharmacyChecker-accredited online pharmacies. Advair (fluticasone / salmeterol) is a prescription combination inhaler used to treat asthma and chronic obstructive pulmonary disease. Insurance coverage for Advair varies widely by plan type. Medicaid covers a plurality of enrollees. On average, Advair can cost around $ 292.22. But you can save on the brand-name and generic versions of the medication by using a GoodRx coupon. Fluticasone/salmeterol is a generic inhaler prescribed for asthma and COPD. It's available as the brand-name drugs Advair Diskus and Advair HFA. Advair contains a combination of the drugs fluticasone and salmeterol, also available in generic form. Advair is supplied as an oral inhalant powder and liquid solution to be inhaled by mouth using a special inhaler. Advair is used to treat asthma and COPD. Find out about cost, financial and insurance assistance, and more. 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