Prices Coupons Patient assistance Xifaxan (rifaximin) is a member of the miscellaneous antibiotics drug class and is commonly used for Diarrhea, Hepatic Encephalopathy, Irritable Bowel Syndrome, and others. The cost for Xifaxan 550 mg oral tablet is around $4,339 for a supply of 60 tablets, depending on the pharmacy you visit. Compare prices and print coupons for Xifaxan and other drugs at CVS, Walgreens, and other pharmacies. Prices start at $3,078.87 Get the best price on Xifaxan at pharmacies near you with SingleCare. Save up to 80% with our Xifaxan coupons – with or without insurance! Xifaxan prices from $416.75. Compare mail-order and cash prices at 60,000+ US pharmacies with a free Rx.com coupon — no insurance needed. Rifaximin FAQs How much does Rifaximin cost without insurance? Rifaximin is quite expensive without insurance coverage, costing around $491.76. Customers who use a SingleCare Rifaximin coupon can pay as low as $451.88 for their prescription. Use your free SingleCare coupon for your prescription at pharmacies near you such as Target, Kroger, and … A Cheaper Xifaxan and the Costs That Sit Beside It A single drug's price falling by 63% does not touch the separate hospital and specialist costs that often accompany advanced liver disease, and a person managing hepatic encephalopathy is rarely dealing with Xifaxan's price alone. The same Medicare system that just lowered this one drug's price still runs prior-authorization rules and … Free tool to compare prescription prices across pharmacies and discount programs. No account or insurance needed. Prices vary by pharmacy. Get the facts on cost and Xifaxan, how the generic compares with the brand name, what financial assistance may be available, and more. Xifaxan (rifaximin) lists at about $2,696 for 30 days. Medicare's negotiated price is $1,000 from January 1, 2027, 63% lower. See what that changes for your copay, coverage rules, and how to pay less. How much does Xifaxan cost with The Rx Advocates? With The Rx Advocates, patients pay a fixed monthly service fee, which depends on the number of medications covered. 1 Medication (Xifaxan only) – $80 per month 2 Medications (Xifaxan + 1 other) – $90 per month 3 Medications (Xifaxan + 2 others) – $100 per month 4+ Medications – $110 per … Xifaxan without insurance costs $70 per tablet, or $421 for six 550 mg tablets. Here's how to save. Medicare coverage and pricing details for Xifaxan. Learn more about Medicare prescription drug plans and savings with GoodRx. Xifaxan is a prescription drug used to treat some types of diarrhea and certain other conditions. Learn about the drug's cost, how to find savings, and more. As seen in the table, the cost of Xifaxan can be quite high, especially if you are purchasing it without insurance. However, by using coupons, insurance, or opting for a generic version like Rifaximin, you can significantly lower your out-of-pocket expenses. Xifaxan Generic Cost: Save with Rifaximin One of the most effective ways to save on your Xifaxan prescription is to purchase its generic … The average cost is over $2500 for a 14-day course treatment (#42 tablets) of Xifaxan 550 mg. If your insurance company does not pay for Xifaxan, talk with your healthcare provider to see if there is an alternative drug that is covered that might be right for you. How can you save money on Xifaxan? Order from Universal Drugstore (UDS) Learn about Xifaxan (rifaximin) usage and dosing. Read the latest news and reviews about the drug as well as potential side effects and popular alternatives. Xifaxan (rifaximin) Savings – ordering the generic from abroad With Xifaxan projected to enjoy patent protection until 2029, cost relief through generic competition isn't exactly around the corner domestically. However, the generic is available to order online from pharmacies located overseas, specifically in India. Compare generic Xifaxan (rifaximin) 550 mg prices from verified online pharmacies or local U.S. pharmacies. Free coupons for generic Xifaxan (rifaximin). Discounts up to 80% off the retail price. Xifaxan costs about $461 for six tablets. Learn how the Xifaxan coupon, Xifaxan savings card, and other tools can help you save. Find the lowest prices for Xifaxan at pharmacies near you. Get free RxSaver coupons and save up to 80% on your prescription. RIFAXIMIN (ri FAX i men) treats diarrhea caused by bacteria. It may also be used to treat irritable bowel syndrome (IBS) with diarrhea. It can be used to prevent hepatic encephalopathy, a condition where the liver does not clear toxins from the body. It works by killing or preventing the growth of bacteria in your intestines that make toxins. It belongs to a group of medications called … How much would Xifaxan cost without insurance? Without insurance, a 30-day supply (90 tablets) of Xifaxan 550mg typically costs $5,000-$5,300 at U.S. pharmacies. Therefore, people usually must pay out-of-pocket. Xifaxan and its generic can be purchased at a lower cost from pharmacies in Canada and other countries. People can easily save money on Xifaxan 550 mg by comparing Xifaxan prices at Canadian and international online pharmacies. Xifaxan sold in the U.S. is manufactured in Canada. Learn more about Xifaxan pricing, uses, and interactions. WellRx helps you find the cheapest pharmacy deals and drug savings. How much does Xifaxan cost without insurance? Without insurance, Xifaxan 550 mg costs approximately $1,600 to $2,200 for a 30-day supply (60 tablets) for hepatic encephalopathy. From the Guidelines The cost of Xifaxan (Rifaximin) without insurance is approximately $2586 for sixty 550-mg tablets 1. Cost Breakdown This cost is based on the average retail cost of the drug, as reported in a study published in the JAMA Network Open 1. RIFAXIMIN (ri FAX i men) treats diarrhea caused by bacteria. It may also be used to treat irritable bowel syndrome (IBS) with diarrhea. It can be used to prevent hepatic encephalopathy, a condition where the liver does not clear toxins from the body. It works by killing or preventing the growth of bacteria in your intestines that make toxins. It belongs to a group of medications called … Xifaxan prices are a financial barrier for many—it can cost well over $2000-$3000 on U.S. retail markets for people without insurance. Insurance and manufacturer assistance programs provide some relief, but most have strict eligibility requirements. The Xifaxan cost in the United States is often high, with many patients paying thousands for a short course. Understanding why it costs so much and what legal savings options exist can help patients and providers plan smarter treatment decisions. Research shows that the average cost of rifaximin for IBS-D is $1,250.76 for a two-week course with insurance, and the total cost can approach $3,000 … Xifaxan (rifaximin) is commonly used for the following conditions. Treatment of travelers' diarrhea (TD), an intestinal infection caused by eating or drinking contaminated food or water. Checking your browser before accessing pmc.ncbi.nlm.nih.gov … Find information about patient assistance and insurance coverage for Xifaxan for IBS-D. See Important Safety Info and Full Prescribing Information. palmettopharm.com How much does Xifaxan cost without insurance? With an average retail price of $2,000 for 30 pills, Xifaxan 550 mg tablets average about $66 each. Fortunately, most people will not need months of treatment. Traveler's diarrhea requires twice-daily dosing for three days (six tablets). IBS-D requires three tablets a day for 14 days (42 tablets). Image: How much does Xifaxan cost with insurance? Xifaxan costs may vary depending on the individual's insurance coverage. The exact cost depends on factors such as health plan, deductible, and pharmacy chosen. Most insurance plans cover at least a portion of Xifaxan's cost; however, it is recommended to check with the health insurer prior to purchase in order to determine out-of-pocket … Xifaxan cost runs $2,350-$3,950 for 60 tablets at U.S. retail in 2026. See real prices by condition, what the new generic means, and how to pay less. How much does Xifaxan cost? Pricing based on 550 MG (quantity 60 tablets). Refine your search Show the coupon above at a pharmacy of choice and get savings on your medication. Image: How much does Xifaxan cost without insurance? Xifaxan typically costs between $1,000 and $2,500 without insurance. The exact cost will depend on the dosage and number of pills prescribed by a doctor. Prices may also vary depending on where it is purchased. Generic versions of Xifaxan may be more affordable than brand-name options. How much does Rifaximin cost without insurance? Without insurance, Rifaximin typically costs between $1,800 and $2,400 for a 30-day supply of 550 mg tablets. Prices vary significantly by pharmacy, so shopping around is essential. Discount cards from GoodRx, SingleCare, or RxSaver can reduce cash prices by 20-40% at participating pharmacies. Xifaxan, a brand name for rifaximin, is a prescription antibiotic that primarily treats certain digestive issues. It is especially known for its effectiveness against traveler's diarrhea and irritable bowel syndrome. Given its growing popularity and critical role in treating these conditions, understanding the cost of Xifaxan is essential for patients and caregivers alike. The cost of …