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It works by increasing the amount of serotonin, a natural substance in the brain that helps maintain mental balance. Celexa (citalopram) is a brand-name drug that's used to treat depression in adults. Celexa comes as a tablet that you swallow. Learn about side effects, dosage, uses, and more. Citalopram (Celexa) is an inexpensive drug used to treat depression. It is slightly less popular than comparable drugs. This drug is available in generic and brand versions. Generic citalopram is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may lower. With the Patient Assistance Program from PAN Foundation, contact the program to see how they can … Citalopram is a SSRI (Selective Serotonin Reuptake Inhibitor) and belongs to a group of medicines called antidepressants. Depression is linked to a s… Citalopram Tablets Citalopram is a medication that treats depression. It increases the amount of serotonin in your brain. This hormone helps regulate your mood. 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